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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A1
All Species:
18.18
Human Site:
S626
Identified Species:
36.36
UniProt:
O95782
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95782
NP_570603.2
977
107546
S626
K
K
G
P
G
A
G
S
A
L
D
D
G
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115458
977
107553
S626
K
K
G
P
G
A
G
S
A
L
D
D
G
R
R
Dog
Lupus familis
XP_541490
922
101289
A606
A
D
L
L
G
L
R
A
A
P
P
P
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P17426
977
107646
S626
K
K
G
P
G
A
A
S
A
L
D
D
S
R
R
Rat
Rattus norvegicus
P18484
938
104026
T625
K
K
G
P
S
T
V
T
D
L
E
E
T
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
T625
K
K
G
P
G
T
V
T
D
L
E
E
I
K
K
Frog
Xenopus laevis
NP_001089303
939
104392
I626
K
K
G
P
S
T
V
I
D
L
E
D
T
K
K
Zebra Danio
Brachydanio rerio
XP_001922441
959
106027
S626
K
K
G
P
G
A
V
S
V
N
E
L
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
E626
K
K
P
G
R
V
P
E
N
E
I
R
E
S
K
Honey Bee
Apis mellifera
XP_394621
937
104937
E626
K
K
P
G
R
V
P
E
N
E
I
R
E
S
K
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
I625
S
K
P
Q
L
E
E
I
E
R
E
E
K
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
T688
L
P
A
S
A
G
S
T
T
L
I
N
T
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
91.3
N.A.
98.4
79.4
N.A.
N.A.
79.5
78.3
82.1
N.A.
66.6
68
62.2
N.A.
Protein Similarity:
100
N.A.
99.8
92.7
N.A.
98.8
86.9
N.A.
N.A.
87.4
87
88.1
N.A.
77.8
78.8
74.9
N.A.
P-Site Identity:
100
N.A.
100
13.3
N.A.
86.6
40
N.A.
N.A.
40
40
46.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
86.6
66.6
N.A.
N.A.
73.3
60
53.3
N.A.
20
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
34
9
9
34
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
25
0
25
34
0
0
0
% D
% Glu:
0
0
0
0
0
9
9
17
9
17
42
25
25
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
59
17
50
9
17
0
0
0
0
0
17
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
17
0
0
25
0
9
0
0
% I
% Lys:
75
84
0
0
0
0
0
0
0
0
0
0
9
25
42
% K
% Leu:
9
0
9
9
9
9
0
0
0
59
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
9
0
9
0
0
0
% N
% Pro:
0
9
25
59
0
0
17
0
0
9
9
9
0
9
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
9
0
0
9
0
17
0
25
34
% R
% Ser:
9
0
0
9
17
0
9
34
0
0
0
0
9
17
9
% S
% Thr:
0
0
0
0
0
25
0
25
9
0
0
0
25
0
0
% T
% Val:
0
0
0
0
0
17
34
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _